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Compound Solutions x Just Ingredients Podcast: Gut Health, Absorption and Butyrate

Compound Solutions x Just Ingredients Podcast on gut health, absorption, and butyrate (CoreBiome®)
February 23, 2026

If supplements are more than a label claim, the real question is simple: can your body actually use what you’re taking? That’s the lens Compound Solutions CEO, Matt Titlow, brings to the Just Ingredients Podcast, with a big spotlight on gut health, absorption, delivery and why butyrate keeps showing up in the conversation.

 

Watch the episode

 

What They Talked About

Absorption and Bioavailability

Gut-Dysfunction Signals

Butyrate, Fiber and Leaky Gut

CoreBiome®

What supplements should you take?

NAD3® and Berberine

Simple Steps for Gut Health

 

What is CoreBiome®?

CoreBiome® is a patented tributyrin (butyrate triglycerides) ingredient designed to deliver butyrate to the colon, supporting gut lining integrity and the gut barrier. That gut barrier support is part of the broader conversation around intestinal permeability, oftentimes referred to as leaky gut. Just Ingredients uses CoreBiome® in their 3-in-1 ProBiotic Complex product, aimed at reversing leaky gut.

 

Why butyrate form matters

Not all butyrate is the same in how it behaves through digestion. Tributyrin (butyrate triglycerides) is discussed as a practical format of butyrate that reaches the colon, which is why it shows up in conversations about absorption and delivery.

 

Trend check: NAD and berberine

The episode also touches on two ingredients that get a lot of attention – NAD and berberine – with a simple reminder: trends are useful, but context matters (goals, fit and why you’re taking it in the first place). Just Ingredients also teamed up with Compound Solutions and used CSI’s NAD3® in their NAD+ Complex, focused on healthy aging and cellular energy.

 

The gut routine basics

Before you add “more” to your gut routine, get the fundamentals right:

  • Fiber-first choices

  • Movement you can repeat

  • Supplements that prioritize bioavailability, not just ingredients lists

 

Links to the full podcast

Apple Podcasts

Spotify

iHeartRadio

 

Keep learning: butyrate + gut barrier basics

Want to go deeper on butyrate, delivery and gut barrier support? Here are a few quick reads from our team:

 

Want to formulate with CoreBiome® or NAD3®?

Let’s talk applications, dosing and formulations. Reach out to us at sales@compoundsolutions.com and we’ll help you build a gut health formula or healthy aging product that delivers!

 

 

 

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