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Category: Formulation

CoreBiome® capsule formulation featuring tributyrin (butyrate triglycerides)

How to Formulate With CoreBiome®: Dose, Capsule Formats and What Brands Ask First

February 25th, 2026

In one sentence: CoreBiome® is a patented tributyrin (butyrate triglycerides) designed to deliver butyrate to the colon, built for capsule-based gut formulas that stay simple to make, simple to take and simple to explain. Also known as: CoreBiome® tributyrin, tributyrin, butyrate triglyceride, tributyrate, postbiotic butyrate, SCFA butyrate Key facts: CoreBiome® is like “vegetables in a […]

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Vegetables in a capsule concept for supporting butyrate production through fermentation

Vegetables in a Capsule: CoreBiome® and the “Predigested Veggies” Idea

February 20th, 2026

In one sentence: CoreBiome® is a patented tributyrin (butyrate triglycerides) that supports a butyrate-focused gut health routine to help with leaky gut and gut barrier integrity. This is especially helpful while someone works toward more consistent fiber intake. Also known as: vegetables in a capsule, predigested veggies, tributyrin (butyrate triglycerides), tributyrate, butyrate, short-chain fatty acid, […]

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Where to buy OnoSweet sweetener in consumer products

Where to Buy OnoSweet®

February 19th, 2026

OnoSweet® is a patented, natural, zero-calorie sweetener made from fermented rice. It brings clean sweetness to modern wellness products without bitterness or a lingering finish, helping brands create sugar-free formulas that still taste craveable. Below is a growing list of products where you can find OnoSweet®. OnoSweet® is supplied as an ingredient to brands and […]

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Prebiotics probiotics and postbiotics explained with butyrate as a key postbiotic style output

Postbiotics Explained: Prebiotics vs Probiotics vs Postbiotics

February 6th, 2026

In one sentence: Prebiotics feed beneficial microbes, probiotics add live strains, and postbiotics are the beneficial outputs, with butyrate being one of the most valuable postbiotics for foundational gut support. Also known as: postbiotics, postbiotic supplements, prebiotics vs probiotics vs postbiotics, butyrate postbiotic, postbiotic butyrate, prebiotics, probiotics, postbiotics Key facts: fiber and resistant starch can […]

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CoreBiome® powder featuring tributyrin (butyrate triglycerides) for gut foundation support

CoreBiome® 101: Patented Tributyrin (Butyrate Triglycerides) for the Gut-Body Axis

January 23rd, 2026

In one sentence: CoreBiome® is a patented tributyrin (butyrate triglycerides) ingredient positioned to deliver butyrate to the colon, supporting gut health and lining, regularity and a healthy inflammatory response. Also known as: CoreBiome® tributyrin, butyrate triglyceride, tributyrate, butyrate (short-chain fatty acid; SCFA), postbiotic butyrate Key facts: “vegetables in a capsule”; fermentation produces butyrate; gut lining […]

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egetables and fiber-rich foods that support fermentation and butyrate production in the gut

What Is Tributyrin? Butyrate Triglycerides Explained

January 14th, 2026

In one sentence: Tributyrin (butyrate triglycerides, also called tributyrate) is a triglyceride form of butyrate used in supplements to help deliver butyrate to the colon, where butyrate supports gut lining integrity. Also known as: tributyrin, butyrate triglycerides, tributyrate, butyrate supplement, postbiotic butyrate, CoreBiome® Key facts: vegetables and resistant starch ferment in the colon and produce […]

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Rice panicle macro — rice-sourced ingredients for precision-fermented Reb M (stevia-free)

Not All Reb M Is Created Equal: Why Source Matters (Rice vs Stevia vs Cane/Corn)

December 2nd, 2025

In one sentence: Source shapes finish. Fermented Reb M (e.g., OnoSweet®) from rice delivers a clean, balanced sweetness curve with fewer bitter byproducts than stevia-leaf or cane/corn.Also known as: Reb M; fermented Reb M; stevia-free Reb M; OnoSweet®Key facts: stevia-free; Non-GMO (OnoSweet®); zero glycemic response; consistent lot-to-lot; sustainable Use cases: Marketers – “source-matters” story and stevia-free […]

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Gummies macro — applications for rice-sourced, precision-fermented Reb M with a clean, balanced sweetness curve

Going Stevia-Free? Meet Reb M from Rice

November 24th, 2025

In one sentence: As labels trend stevia-free, brands are choosing fermented Reb M from rice, delivering a clean, balanced sweetness curve and consistent quality.Also known as: stevia-free Reb M; rice-sourced Reb M; fermented Reb M; OnoSweet®Key facts: stevia-free – Non-GMO (example: OnoSweet®) – zero glycemic response – consistent lot-to-lotUse cases: Marketers – stevia-free positioning, cleaner […]

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Rice plant close-up — source of ingredients used to produce stevia-free Reb M via precision fermentation

Reb A vs Reb M – What’s the Difference, and Why it Matters for Taste

November 19th, 2025

In one sentence: Reb A often reads sharper with a lingering finish, while Reb M presents a cleaner, more balanced sweetness curve, especially when produced via precision fermentation using rice-sourced ingredients.Key facts: stevia-free options exist; different steviol glycosides; distinct sensory arcs; source/pathway affect finish; Non-GMO example (OnoSweet®)Use cases: proteins; hydration/RTDs; gummies; soft chews; functional foodsLearn […]

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Precision fermentation – non-GMO microbes convert rice-sourced ingredients into stevia-free Reb M (OnoSweet®). ow rice-sourced ingredients become stevia-free Reb M via precision fermentation – Non-GMO, consistent performance.

Fermentation for Reb M – How Rice Becomes Stevia-Free Reb M

November 14th, 2025

In one sentence: Food-grade microbes convert rice-sourced ingredients into Reb M via fermentation, enabling stevia-free labeling with a clean, balanced sweetness curve.Also known as: Reb M from rice-sourced ingredients; fermented Reb M; fermentation-derived Reb M; Reb M from riceKey facts: stevia-free; zero glycemic response; batch-to-batch consistency; scalable supplyUse cases: proteins; hydration/RTDs; gummies; soft chews; functional […]

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OnoSweet® zero-calorie fermented rice sweetener, Non-GMO

OnoSweet® – Natural, Zero-Calorie Sweetness from Fermented Rice

November 12th, 2025

In one sentence: OnoSweet® is a patented, natural, zero-calorie sweetener made from fermented rice, delivering clean sweetness with no bitter or lingering aftertaste and zero glycemic response.Also known as: fermented rice sweetener, rice fermented sweetener, natural zero-calorie sweetener, stevia free sweetenerKey facts: stevia free, not derived from the stevia plant, Non-GMO, zero glycemic response, scales […]

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Article: Is Sugar the Next Cigarette?

Is Sugar the New Cigarette? Plus: How to Respond to this Market Demand

May 28th, 2024

Coca-Cola wouldn’t market Coke Zero if it weren’t making money from the “zero -sugar” movement. We’re shifting away from sugar like we’ve shifted away from cigarettes. Learn more about sugar’s impact on the market.   Here are some sugar-substitute sweetening ingredients that just don’t make the cut: Sucralose and Ace-K are synthetic Monk fruit isn’t […]

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The only butyrate that is made by fermentation in the USA

CoreBiome® is Now Fermented and Made in the USA

May 9th, 2024

It has been five years since we introduced CoreBiome®, our patented, bioavailable, postbiotic butyrate, to the market, and it has been the foundational ingredient for innovative gut health products globally. We have proudly partnered with brands like Gundry MD, Ritual, Beekeepers Naturals and more to deliver meaningful results to consumers everywhere. This has all been […]

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Best Self starts with Caffeine TeaCrine Dyanmine

Your Customer’s Best Self Starts with a Unique, Patented Combination

December 21st, 2023

New research tells a compelling performance story that resonates with go-getters and good-energy seekers everywhere–your customers. The data show that CTD can boost mental stamina, reaction time, focus and precision during intense cognitive challenges – exactly what’s needed to excel in today’s fast-paced, distraction-filled world.

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DDDA Metabolyte™

Introducing Metabolyte™

December 13th, 2023

DDDA (as Metabolyte™) is not a protein, carbohydrate, fat or ketone. It’s a “fifth macronutrient” – a dicarboxylic acid. DDDA contains approximately seven calories per gram, so it’s calorie content fits between a typical carbohydrate (~four calories/gram) and a fat (~nine calories/gram). This means DDDA is relatively energy dense, but without the downsides of higher […]

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DDDA as Metabolyte™

What types of DDDA are there?

July 24th, 2023

Dodecanedioic acid (DDDA) (as patent-pending Metabolyte™) comes in powder form as sodium dodecanedioic acid and potassium dodecanedioic acid. They dissolve easily in water for powder and stick pack dosage forms. Sodium and potassium are the two most important electrolytes for several reasons:   Sodium dodecanedioic acid is NOT sodium chloride (salt). Sodium Metabolyte™ is a […]

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How to formulate with DDDA (as Metabolyte™)

How do I formulate with Dodecanedioic Acid (DDDA)?

July 24th, 2023

Dodecanedioic acid (DDDA) (as patent-pending Metabolyte™) comes in powder form, so it’s ideal for powder-into-water applications like hydration, pre workouts, and weight management powders. Metabolyte™ comes in two forms: potassium DDDA and sodium DDDA. The recommended dosing is 1.5g to 3g of total material. It’s possible to go higher for more acute benefits, but 1.5g […]

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DDDA Metabolyte™ Weight Management

Does DDDA support metabolism and weight management?

July 24th, 2023

For dodecanedioic acid (DDDA) (as patent-pending Metabolyte™), research in animals and humans have shown improvements in metabolism and weight management. Metabolic Health Dodecanedioic acid (DDDA) (as patent-pending Metabolyte™) has been shown in animal models to not just maintain insulin levels in already healthy ranges, but to also sensitize cells to insulin. This is fundamental to […]

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