TeaCrine® & Caffeine—Simply Unbeatable
If you’re like most people, your day starts pretty much the same — roll out of bed and straight into the kitchen for a much-needed cup of coffee.
What is it about coffee that’s so warm, comforting, and refreshing? Why is it the go-to way to start your day?
Well, some of it has to do with the actual ritual of brewing the coffee and sitting down to sip it while reading the paper or on the way to work. But, the vast majority of people making coffee their way to begin each morning due to the caffeine contained in each cup of coffee.
But can we make caffeine better?
Quite simply, yes, you can!
Caffeine, Glorious Caffeine
Caffeine really needs no introduction, it’s the most popular, and widely consumed, drug on the face of the planet found all over the place. It literally is EVERYWHERE—from coffee to energy drinks and even peanut butter and whey protein powder.
Why is this?
Simply put, caffeine is awesome. It wakes you up, clears brain fog, enhances mood, alertness, and productivity.  It’s also a valuable performance enhancer for exercise, improving cardiovascular endurance/stamina, and in some studies, reaction time and strength. [2,3]
But, not all is rosy when it comes to the effects of caffeine. There are a few limitations or “problems” with consuming caffeine:
– Tolerance Build Up
– Disrupted Sleep
Given these considerations, how do we get caffeine without the downsides?
The way to make caffeine work better, or “get more” from your caffeine fix, is by combining it with one of its chemical cousins called TeaCrine®.
What is TeaCrine®?
TeaCrine® is a purine alkaloid similar in structure to caffeine found naturally in certain species of coffee, exotic fruits, and kucha tea.
TeaCrine® also mimics the way caffeine functions in the body to a certain extent. Like caffeine, TeaCrine® also inhibits adenosine receptors,  which improves energy and alertness.
However, that’s about the only similarity between these two energy-boosting molecules.
TeaCrine® also activates dopamine receptors, [5,6] leading to improved mood and motivation to exercise, giving TeaCrine® some additional nootropic benefits you wouldn’t get with caffeine alone. On top of that, there are a few other reasons TeaCrine® should be added to your daily supplement regimen, especially if you’re sick of caffeine:
Unique Benefits of TeaCrine®
– TeaCrine® is non-habit forming!
Even after 8 weeks of daily supplementation (at 300mg/day), TeaCrine® does not lead to dependency, tolerance build up, or withdrawal as is common with caffeine and other stimulants. 
With TeaCrine®, you get the same results (energy, mood, concentration, etc.) every time, without having to continually increase the dose!
– TeaCrine® does not negatively affect the cardiovascular system.
Many people feel uncomfortable using caffeine, frequently citing a “heart racing” or “jittery” sensation. This is due to the fact that caffeine (and other stimulants) can increase heart rate and blood pressure. 
TeaCrine®, on the other hand, is able to increase mental energy and reduce fatigue without stimulating the cardiovascular system. In other words, you get the boost in energy and alertness without feeling like your chest is going to explode!
– TeaCrine® is crash- and jitter-free.
Perhaps the best reason to use TeaCrine® is that it does not result in the inevitable energy crash that comes with caffeine. Imagine being free of the afternoon dip in energy levels that often results from coming off a caffeine high.
Suffice to say that TeaCrine® is pretty awesome on its own, but an obvious question is what happens when you combine caffeine + TeaCrine®?
Research presented in the 14th International Society of Sports Nutrition (ISSN) Conference provided convincing evidence that combining TeaCrine® + caffeine:
– Improved exercise capacity and endurance.
Combining TeaCrine® (125mg) + caffeine (150mg) together led to greater exercise capacity than consuming either caffeine alone (275mg) or placebo. 
TeaCrine® + caffeine together helped sustain focus and concentration under fatiguing conditions better than caffeine alone. 
-Heightens alertness, attention, and information processing.
Stacking caffeine + TeaCrine® led to better performance compared to caffeine alone or placebo on complex choice, reaction time tests. 
So, why is caffeine + TeaCrine® so effective?
Caffeine Enhances Effects of TeaCrine®
Emerging research has confirmed what many TeaCrine® users have been saying for a few years now — caffeine + TeaCrine® is a winning combination!
Essentially, combining TeaCrine® with caffeine enhances TeaCrine® absorption and utilization by the body,[7,8] delivering stronger, more powerful results, i.e. tighter focus, more dialed-in concentration, and longer-lasting energy.
This occurs because when you mix caffeine with TeaCrine®, maximum plasma concentrations of TeaCrine® increase to a higher extent than when TeaCrine® is ingested all by itself. In addition, published research has also shown that adding TeaCrine® to caffeine does not negatively affect the way caffeine works in the body. 
In other words, adding caffeine to TeaCrine® makes the two work better!
Caffeine + TeaCrine® — A Winning Combo
There’s no denying that caffeine and TeaCrine® are awesome in their own right. Alone, each has the power to ignite your mind and power your performance to new levels of excellence, but when combined, the two form a pair that deliver results greater than the sum of their parts making you better mentally and physically for hours on end!
To begin formulating with TeaCrine®, contact us with some details about your project.
To learn more about this incredible energy, mood, motivation, focus ingredient, click here.
To find pure TeaCrine® online, or inside a powerful formula, browse our featured products.
1. Goldstein ER, Ziegenfuss T, Kalman D, et al. International society of sports nutrition position stand: caffeine and performance. Journal of the International Society of Sports Nutrition. 2010;7:5. doi:10.1186/1550-2783-7-5.
2. Grgic J, Trexler ET, Lazinica B, Pedisic Z. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2018;15(1):11. doi: 10.1186/s12970-018-0216-0.
3. Smit HJ, Rogers PJ. Effects of low doses of caffeine on cognitive performance, mood and thirst in low and higher caffeine consumers. Psychopharmacology (Berl). 2000;152(2):167-173.
4. Magkos F, Kavouras SA. Caffeine use in sports, pharmacokinetics in man, and cellular mechanisms of action. Crit Rev Food Sci Nutr. 2005;45(7-8):535-562. doi:10.1080/1040-830491379245.
5. Taylor L, Mumford P, Roberts M, et al. Safety of TeaCrine®, a non-habituationg, naturally-occuring purine alkaloid over eight weeks of continuous use. J Int Soc Sports Nutr. 2-16;13(1):1-14. doi:10.1186/s12970-016-0113-3.
6. Feduccia AA, Wang Y, Simms JA, Yi HY, Li R, Bjeldanes L, et al. Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors. Pharmacol Biochem Behav 2012;102(2):241-248.
7. Access O. Proceedings of the Fourteenth International Society of Sports Nutrition (ISSN) Conference and Expo. J Int Soc Sports Nutr. 2017;14(s2):31. doi:10.1186/s12970-017-0188-5.
8. He H, Ma D, Crone LB, et al. Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans. J Caffeine Res. 2017;7(3):95-102. doi:10.1089/jcr.2017.0006.
9. Geethavani G, Rameswarudu M, Reddy R. Effect of Caffeine on Heart Rate and Blood Pressure. Int J Sci Res Publ. 2014;4(2):1-4.
10. Wang Y, Yang X, Li J, Ye C, Song X. Theacrine, a purine alkaloid with anti-inflammatory and analgestic activities. Fitoterapia. 2010;81)6):627-631. doi: https://doi.org/10.1016/j.fitote.2010.03.008.Back to Blog