Does DDDA support hydration?
A resounding “YES!” According to Dr. Andrew Huberman, the best nootropic is healthy, adequate sleep. The second best is hydration. Even mild dehydration can limit cognitive function. So, can we just drink water to hydrate and improve cognitive function? Absolutely. This article is about optimizing hydration above water.
We can drink a lot of filtered water, and that’s great. But if you want to optimize your hydration, you’d ensure some electrolytes were present in your water. Arguably the best electrolyte foundation is with sodium and potassium. The reason we use sodium and potassium Metabolyte™ in hydration mixes is because of the active dodecanedioic acid (DDDA). That is the active component. Then layer in magnesium citrate, calcium citrate and trace minerals, for example.
Strategies differ with the sodium and potassium ratio. For example, you see LMNT with a 5:1 sodium-potassium ratio and no sugar. Liquid I.V. has a 1:1.3 sodium:potassium ratio and 11 grams of sugar. And Ultima flips the ratio using more potassium in a potassium:sodium ratio of 5:1, no sugar, and more of the other electrolytes. Gatorade contains a roughly 3:1 sodium:potassium ratio with very low levels of potassium; and now Gatorlyte contains a significantly different ~1.5:1 ratio and a large 800% increase in potassium levels over original Gatorade. Now PRIME is using coconut water for its hydration complex.
In 2011, Harvard Health mentioned our ancestors consumed far more potassium than sodium because they consumed far more vegetables than we do now. They also discuss the fact that talking about the minerals in isolation is mistaken because the ratio is what is important.
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And here’s Harvard Health’s follow-up article on the value of potassium (and sodium) for heart health given potassium is the most deficient mineral in the American diet.
Because nearly 100% of Americans are potassium deficient, leading with potassium isn’t a bad option.
Where is DDDA found?
Dodecanedioic acid (DDDA) (as Metabolyte™) is found in some plants such as green beans (Phaseolus vulgaris). Other dicarboxylic acids can be found in castor oil, for example. Because DDDA is found in low concentrations in nature, the only practical way to obtain DDDA is through supplementation like patent-pending Metabolyte™. And only Metabolyte is self-affirmed Generally Recognized As Safe (GRAS) and regulatorily compliant.
Compound Solutions is pioneering this “supercharged MCT” called Metabolyte™ in dietary supplements. Learn more below.
Connection to DDDA and sports nutrition and hydration research
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